The SBHD conference series is a binational annual event initially launched by Peter Sorger and colleagues at Harvard Medical School in 2008 with its location alternating between the USA and Germany. SBHD 2026 will take place in Boston, USA hosted by The Institute of Experiential AI at Northeastern University. The Systems Biology of Human Disease (SBHD) conference focuses on systems biology approaches for the understanding, diagnosis, and treatment of human diseases.