CLEARPLASMA ClearPlasma™ effectively reduces bleeding in more than 55%The ClearPlasma device is a non-pyrogenic, sterile, single-use device designed to remove Plasminogen and tPA from blood products, thus enabling the reduction of fibrin clot breakdown (fibrinolysis) occurring during massive bleeding. The device utilizes the chemical affinity of plasminogen to a specific ligand through its binding sites.